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Deficits in a Simple Visual Go/No-go Discrimination Task in Two Mouse Models of Huntington’s Disease

Huntington’s disease (HD), a devastating neurodegenerative disorder caused by a CAG repeat expansion on the HTT gene located on chromosome 4, is associated with a characteristic pattern of progressive cognitive dysfunction known to involve early deficits in executive function. A modified Go/No-go su...

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Detalles Bibliográficos
Autores principales: Oakeshott, Stephen, Farrar, Andrew, Port, Russell, Cummins-Sutphen, Jane, Berger, Jason, Watson-Johnson, Judy, Ramboz, Sylvie, Howland, David, Brunner, Dani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828223/
https://www.ncbi.nlm.nih.gov/pubmed/24270512
http://dx.doi.org/10.1371/currents.hd.fe74c94bdd446a0470f6f905a30b5dd1