Decrease in Prosaposin in the Dystrophic mdx Mouse Brain

BACKGROUND: Duchenne muscular dystrophy caused by a mutation in the X-linked dystrophin gene induces metabolic and structural disorders in the brain. A lack of dystrophin in brain structures is involved in impaired cognitive function. Prosaposin (PS), a neurotrophic factor, is abundant in the choroi...

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Detalles Bibliográficos
Autores principales: Gao, Hui-ling, Li, Cheng, Nabeka, Hiroaki, Shimokawa, Tetsuya, Kobayashi, Naoto, Saito, Shouichiro, Wang, Zhan-You, Cao, Ya-ming, Matsuda, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828254/
https://www.ncbi.nlm.nih.gov/pubmed/24244600
http://dx.doi.org/10.1371/journal.pone.0080032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828254/
https://www.ncbi.nlm.nih.gov/pubmed/24244600
http://dx.doi.org/10.1371/journal.pone.0080032

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