Triptolide Induces Growth Inhibition and Apoptosis of Human Laryngocarcinoma Cells by Enhancing p53 Activities and Suppressing E6-Mediated p53 Degradation

Triptolide, an active compound extracted from Chinese herb Leigongteng (Tripterygium wilfordii Hook F.), shows a broad-spectrum of anticancer activity through its cytotoxicity. However, the efficacy of triptolide on laryngocarcinoma rarely been evaluated, and the mechanism by which triptolide-induce...

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Detalles Bibliográficos
Autores principales: Zhao, Fei, Huang, Weiwei, Ousman, Tamgue, Zhang, Bin, Han, Yangyang, Clotaire, Daguia Zambe John, Wang, Chen, Chang, Huanhuan, Luo, Huanan, Ren, Xiaoyong, Lei, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828261/
https://www.ncbi.nlm.nih.gov/pubmed/24244715
http://dx.doi.org/10.1371/journal.pone.0080784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828261/
https://www.ncbi.nlm.nih.gov/pubmed/24244715
http://dx.doi.org/10.1371/journal.pone.0080784

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