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Triptolide Induces Growth Inhibition and Apoptosis of Human Laryngocarcinoma Cells by Enhancing p53 Activities and Suppressing E6-Mediated p53 Degradation
Triptolide, an active compound extracted from Chinese herb Leigongteng (Tripterygium wilfordii Hook F.), shows a broad-spectrum of anticancer activity through its cytotoxicity. However, the efficacy of triptolide on laryngocarcinoma rarely been evaluated, and the mechanism by which triptolide-induce...
Autores principales: | Zhao, Fei, Huang, Weiwei, Ousman, Tamgue, Zhang, Bin, Han, Yangyang, Clotaire, Daguia Zambe John, Wang, Chen, Chang, Huanhuan, Luo, Huanan, Ren, Xiaoyong, Lei, Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828261/ https://www.ncbi.nlm.nih.gov/pubmed/24244715 http://dx.doi.org/10.1371/journal.pone.0080784 |
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