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Alterations in Ethanol-Induced Behaviors and Consumption in Knock-In Mice Expressing Ethanol-Resistant NMDA Receptors

Ethanol's action on the brain likely reflects altered function of key ion channels such as glutamatergic N-methyl-D-aspartate receptors (NMDARs). In this study, we determined how expression of a mutant GluN1 subunit (F639A) that reduces ethanol inhibition of NMDARs affects ethanol-induced behav...

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Detalles Bibliográficos
Autores principales: den Hartog, Carolina R., Beckley, Jacob T., Smothers, Thetford C., Lench, Daniel H., Holseberg, Zack L., Fedarovich, Hleb, Gilstrap, Meghin J., Homanics, Gregg E., Woodward, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828265/
https://www.ncbi.nlm.nih.gov/pubmed/24244696
http://dx.doi.org/10.1371/journal.pone.0080541