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Acute Activation, Desensitization and Smoldering Activation of Human Acetylcholine Receptors

The behavioral effects of nicotine and other nicotinic agonists are mediated by AChRs in the brain. The relative contribution of acute activation versus chronic desensitization of AChRs is unknown. Sustained “smoldering activation” occurs over a range of agonist concentrations at which activated and...

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Detalles Bibliográficos
Autores principales: Campling, Barbara G., Kuryatov, Alexander, Lindstrom, Jon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828267/
https://www.ncbi.nlm.nih.gov/pubmed/24244538
http://dx.doi.org/10.1371/journal.pone.0079653