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Acute Activation, Desensitization and Smoldering Activation of Human Acetylcholine Receptors
The behavioral effects of nicotine and other nicotinic agonists are mediated by AChRs in the brain. The relative contribution of acute activation versus chronic desensitization of AChRs is unknown. Sustained “smoldering activation” occurs over a range of agonist concentrations at which activated and...
Autores principales: | Campling, Barbara G., Kuryatov, Alexander, Lindstrom, Jon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828267/ https://www.ncbi.nlm.nih.gov/pubmed/24244538 http://dx.doi.org/10.1371/journal.pone.0079653 |
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