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Rab-3 and unc-18 Interactions in Alcohol Sensitivity Are Distinct from Synaptic Transmission

The molecular mechanisms underlying sensitivity to alcohol are incompletely understood. Recent research has highlighted the involvement of two presynaptic proteins, Munc18 and Rab3. We have previously characterised biochemically a number of specific Munc18 point mutations including an E466K mutation...

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Detalles Bibliográficos
Autores principales: Johnson, James R., Kashyap, Sudhanva, Rankin, Kim, Barclay, Jeff W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828271/
https://www.ncbi.nlm.nih.gov/pubmed/24244732
http://dx.doi.org/10.1371/journal.pone.0081117