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Impairments in Neurogenesis Are Not Tightly Linked to Depressive Behavior in a Transgenic Mouse Model of Alzheimer's Disease

Alzheimer's disease (AD), the most common cause of dementia, is also associated with depression. Although the precise mechanisms that lead to depression in AD are unknown, the impairments in adult hippocampal neurogenesis observed in AD may play a role. Adult-born neurons play a critical role i...

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Detalles Bibliográficos
Autores principales: Iascone, Daniel M., Padidam, Sneha, Pyfer, Mark S., Zhang, Xiaohong, Zhao, Lijuan, Chin, Jeannie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828273/
https://www.ncbi.nlm.nih.gov/pubmed/24244537
http://dx.doi.org/10.1371/journal.pone.0079651