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Impairments in Neurogenesis Are Not Tightly Linked to Depressive Behavior in a Transgenic Mouse Model of Alzheimer's Disease
Alzheimer's disease (AD), the most common cause of dementia, is also associated with depression. Although the precise mechanisms that lead to depression in AD are unknown, the impairments in adult hippocampal neurogenesis observed in AD may play a role. Adult-born neurons play a critical role i...
Autores principales: | Iascone, Daniel M., Padidam, Sneha, Pyfer, Mark S., Zhang, Xiaohong, Zhao, Lijuan, Chin, Jeannie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828273/ https://www.ncbi.nlm.nih.gov/pubmed/24244537 http://dx.doi.org/10.1371/journal.pone.0079651 |
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