Proteomic Analysis of Tissue from α1,3-galactosyltransferase Knockout Mice Reveals That a Wide Variety of Proteins and Protein Fragments Change Expression Level

A barrier in a pig-to-man xenotransplantation is that the Galα1-3Galβ1-4GlcNAc-R carbohydrate (α-Gal epitope) expressed on pig endothelial cells reacts with naturally occurring antibodies in the recipient’s blood leading to rejection. Deletion of the α1,3-galactosyltransferase gene prevents the synt...

Descripción completa

Detalles Bibliográficos
Autores principales: Thorlacius-Ussing, Louise, Ludvigsen, Maja, Kirkeby, Svend, Vorum, Henrik, Honoré, Bent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828281/
https://www.ncbi.nlm.nih.gov/pubmed/24244699
http://dx.doi.org/10.1371/journal.pone.0080600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828281/
https://www.ncbi.nlm.nih.gov/pubmed/24244699
http://dx.doi.org/10.1371/journal.pone.0080600

Ejemplares similares