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Pifithrin-μ, an Inhibitor of Heat-Shock Protein 70, Can Increase the Antitumor Effects of Hyperthermia Against Human Prostate Cancer Cells

Hyperthermia (HT) improves the efficacy of anti-cancer radiotherapy and chemotherapy. However, HT also inevitably evokes stress responses and increases the expression of heat-shock proteins (HSPs) in cancer cells. Among the HSPs, HSP70 is known as a pro-survival protein. In this study, we investigat...

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Detalles Bibliográficos
Autores principales: Sekihara, Kazumasa, Harashima, Nanae, Tongu, Miki, Tamaki, Yukihisa, Uchida, Nobue, Inomata, Taisuke, Harada, Mamoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828328/
https://www.ncbi.nlm.nih.gov/pubmed/24244355
http://dx.doi.org/10.1371/journal.pone.0078772