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Structural Features of the Regulatory ACT Domain of Phenylalanine Hydroxylase

Phenylalanine hydroxylase (PAH) catalyzes the conversion of L-Phe to L-Tyr. Defects in PAH activity, caused by mutations in the human gene, result in the autosomal recessively inherited disease hyperphenylalaninemia. PAH activity is regulated by multiple factors, including phosphorylation and ligand...

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Detalles Bibliográficos
Autores principales:	Carluccio, Carla, Fraternali, Franca, Salvatore, Francesco, Fornili, Arianna, Zagari, Adriana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828330/ https://www.ncbi.nlm.nih.gov/pubmed/24244510 http://dx.doi.org/10.1371/journal.pone.0079482

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