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The Development of an Experimental Multiple Serogroups Vaccine for Neisseria meningitidis

A native outer membrane vesicles (NOMV) vaccine was developed from three antigenically diverse strains of Neisseria meningitidis that express the L1,8, L2, and L3,7 lipooligosaccharide (LOS) immunotypes, and whose synX, and lpxL1 genes were deleted.. Immunogenicity studies in mice showed that the va...

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Detalles Bibliográficos
Autores principales: Pinto, Valerian B., Burden, Robert, Wagner, Allyn, Moran, Elizabeth E., Lee, Che-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828347/
https://www.ncbi.nlm.nih.gov/pubmed/24244473
http://dx.doi.org/10.1371/journal.pone.0079304