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High-Frequency Stimulation of Nucleus Accumbens Changes in Dopaminergic Reward Circuit

Deep brain stimulation (DBS) of the nucleus accumbens (NAc) is a potential remedial therapy for drug craving and relapse, but the mechanism is poorly understood. We investigated changes in neurotransmitter levels during high frequency stimulation (HFS) of the unilateral NAc on morphine-induced rats....

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Detalles Bibliográficos
Autores principales: Yan, Na, Chen, Ning, Zhu, Honghua, Zhang, Jianguo, Sim, Moira, Ma, Yu, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828386/
https://www.ncbi.nlm.nih.gov/pubmed/24244479
http://dx.doi.org/10.1371/journal.pone.0079318