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Expression and DNA methylation levels of prolyl hydroxylases PHD1, PHD2, PHD3 and asparaginyl hydroxylase FIH in colorectal cancer

BACKGROUND: Colorectal cancer (CRC) is one of the most common and comprehensively studied malignancies. Hypoxic conditions during formation of CRC may support the development of more aggressive cancers. Hypoxia inducible factor (HIF), a major player in cancerous tissue adaptation to hypoxia, is nega...

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Detalles Bibliográficos
Autores principales: Rawluszko, Agnieszka A, Bujnicka, Katarzyna E, Horbacka, Karolina, Krokowicz, Piotr, Jagodziński, Paweł P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828400/
https://www.ncbi.nlm.nih.gov/pubmed/24195777
http://dx.doi.org/10.1186/1471-2407-13-526