The effects of linkage on comparative estimators of selection

BACKGROUND: A major goal of molecular evolution is to determine how natural selection has shaped the evolution of a gene. One approach taken by methods such as K( A )/K( S ) and the McDonald-Kreitman (MK) test is to compare the frequency of non-synonymous and synonymous changes. These methods, howev...

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Detalles Bibliográficos
Autores principales: Chan, Carmen HS, Hamblin, Steven, Tanaka, Mark M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828407/
https://www.ncbi.nlm.nih.gov/pubmed/24199711
http://dx.doi.org/10.1186/1471-2148-13-244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828407/
https://www.ncbi.nlm.nih.gov/pubmed/24199711
http://dx.doi.org/10.1186/1471-2148-13-244

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