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The effects of linkage on comparative estimators of selection
BACKGROUND: A major goal of molecular evolution is to determine how natural selection has shaped the evolution of a gene. One approach taken by methods such as K( A )/K( S ) and the McDonald-Kreitman (MK) test is to compare the frequency of non-synonymous and synonymous changes. These methods, howev...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828407/ https://www.ncbi.nlm.nih.gov/pubmed/24199711 http://dx.doi.org/10.1186/1471-2148-13-244 |