Genetic rescue of Muenke syndrome model hearing loss reveals prolonged FGF-dependent plasticity in cochlear supporting cell fates

The stereotyped arrangement of cochlear sensory and supporting cells is critical for auditory function. Our previous studies showed that Muenke syndrome model mice (Fgfr3(P244R/+)) have hearing loss associated with a supporting cell fate transformation of two Deiters' cells to two pillar cells....

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Detalles Bibliográficos
Autores principales: Mansour, Suzanne L., Li, Chaoying, Urness, Lisa D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828518/
https://www.ncbi.nlm.nih.gov/pubmed/24145799
http://dx.doi.org/10.1101/gad.228957.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828518/
https://www.ncbi.nlm.nih.gov/pubmed/24145799
http://dx.doi.org/10.1101/gad.228957.113

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