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Coordinate Nodal and BMP inhibition directs Baf60c-dependent cardiomyocyte commitment

A critical but molecularly uncharacterized step in heart formation and regeneration is the process that commits progenitor cells to differentiate into cardiomyocytes. Here, we show that the endoderm-derived dual Nodal/bone morphogenetic protein (BMP) antagonist Cerberus-1 (Cer1) in embryonic stem ce...

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Detalles Bibliográficos
Autores principales: Cai, Wenqing, Albini, Sonia, Wei, Ke, Willems, Erik, Guzzo, Rosa M., Tsuda, Masanao, Giordani, Lorenzo, Spiering, Sean, Kurian, Leo, Yeo, Gene W., Puri, Pier Lorenzo, Mercola, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828519/
https://www.ncbi.nlm.nih.gov/pubmed/24186978
http://dx.doi.org/10.1101/gad.225144.113