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Coordinate Nodal and BMP inhibition directs Baf60c-dependent cardiomyocyte commitment
A critical but molecularly uncharacterized step in heart formation and regeneration is the process that commits progenitor cells to differentiate into cardiomyocytes. Here, we show that the endoderm-derived dual Nodal/bone morphogenetic protein (BMP) antagonist Cerberus-1 (Cer1) in embryonic stem ce...
Autores principales: | Cai, Wenqing, Albini, Sonia, Wei, Ke, Willems, Erik, Guzzo, Rosa M., Tsuda, Masanao, Giordani, Lorenzo, Spiering, Sean, Kurian, Leo, Yeo, Gene W., Puri, Pier Lorenzo, Mercola, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828519/ https://www.ncbi.nlm.nih.gov/pubmed/24186978 http://dx.doi.org/10.1101/gad.225144.113 |
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