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Structural basis for targeting the chromatin repressor Sfmbt to Polycomb response elements

Polycomb group (PcG) protein complexes repress developmental regulator genes by modifying their chromatin. How different PcG proteins assemble into complexes and are recruited to their target genes is poorly understood. Here, we report the crystal structure of the core of the Drosophila PcG protein...

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Detalles Bibliográficos
Autores principales: Alfieri, Claudio, Gambetta, Maria Cristina, Matos, Raquel, Glatt, Sebastian, Sehr, Peter, Fraterman, Sven, Wilm, Matthias, Müller, Jürg, Müller, Christoph W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828522/
https://www.ncbi.nlm.nih.gov/pubmed/24186981
http://dx.doi.org/10.1101/gad.226621.113