Expression of OA1 limits the fusion of a subset of MVBs with lysosomes – a mechanism potentially involved in the initial biogenesis of melanosomes

Multivesicular endosomes/bodies (MVBs) deliver proteins, such as activated EGF receptor (EGFR), to the lysosome for degradation, and, in pigmented cells, MVBs containing PMEL are an initial stage in melanosome biogenesis. The mechanisms regulating numbers and fate of different populations of MVB are...

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Detalles Bibliográficos
Autores principales: Burgoyne, Thomas, Jolly, Rushee, Martin-Martin, Belen, Seabra, Miguel C., Piccirillo, Rosanna, Schiaffino, Maria Vittoria, Futter, Clare E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828590/
https://www.ncbi.nlm.nih.gov/pubmed/24006264
http://dx.doi.org/10.1242/jcs.128561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828590/
https://www.ncbi.nlm.nih.gov/pubmed/24006264
http://dx.doi.org/10.1242/jcs.128561

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