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IgM Repertoire Biodiversity is Reduced in HIV-1 Infection and Systemic Lupus Erythematosus

Background: HIV-1 infection or systemic lupus erythematosus (SLE) disrupt B cell homeostasis, reduce memory B cells, and impair function of IgG and IgM antibodies. Objective: To determine how disturbances in B cell populations producing polyclonal antibodies relate to the IgM repertoire, the IgM tra...

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Detalles Bibliográficos
Autores principales: Yin, Li, Hou, Wei, Liu, Li, Cai, Yunpeng, Wallet, Mark Andrew, Gardner, Brent Paul, Chang, Kaifen, Lowe, Amanda Catherine, Rodriguez, Carina Adriana, Sriaroon, Panida, Farmerie, William George, Sleasman, John William, Goodenow, Maureen Michels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828670/
https://www.ncbi.nlm.nih.gov/pubmed/24298273
http://dx.doi.org/10.3389/fimmu.2013.00373