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IgM Repertoire Biodiversity is Reduced in HIV-1 Infection and Systemic Lupus Erythematosus
Background: HIV-1 infection or systemic lupus erythematosus (SLE) disrupt B cell homeostasis, reduce memory B cells, and impair function of IgG and IgM antibodies. Objective: To determine how disturbances in B cell populations producing polyclonal antibodies relate to the IgM repertoire, the IgM tra...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828670/ https://www.ncbi.nlm.nih.gov/pubmed/24298273 http://dx.doi.org/10.3389/fimmu.2013.00373 |