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Remodeling of Energy Metabolism and Absence of Electrophysiological Changes in the Heart of Obese Hyperleptinemic Mice. New Insights into the Pleiotropic Role of Leptin
Dietary treatment with high-fat diets (HFD) triggers diabetes and hyperleptinemia, concomitantly with a partial state of leptin resistance that affects hepatic and adipose tissue but not the heart. In this context, characterized by widespread steatosis, cardiac lipid content remains unchanged. As pr...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828673/ https://www.ncbi.nlm.nih.gov/pubmed/24298268 http://dx.doi.org/10.3389/fendo.2013.00175 |