Remodeling of Energy Metabolism and Absence of Electrophysiological Changes in the Heart of Obese Hyperleptinemic Mice. New Insights into the Pleiotropic Role of Leptin

Dietary treatment with high-fat diets (HFD) triggers diabetes and hyperleptinemia, concomitantly with a partial state of leptin resistance that affects hepatic and adipose tissue but not the heart. In this context, characterized by widespread steatosis, cardiac lipid content remains unchanged. As pr...

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Detalles Bibliográficos
Autores principales: Guzmán-Ruiz, Rocío, Gómez-Hurtado, Nieves, Gil-Ortega, Marta, Somoza, Beatriz, González, M. Carmen, Aránguez, Isabel, Martín-Ramos, Miriam, González-Martín, Carmen, Delgado, Carmen, Fernández-Alfonso, Marisol, Ruiz-Gayo, Mariano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828673/
https://www.ncbi.nlm.nih.gov/pubmed/24298268
http://dx.doi.org/10.3389/fendo.2013.00175

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