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Par-complex aPKC and Par3 cross-talk with innate immunity NF-κB pathway in epithelial cells

Components of the Par-complex, atypical PKC and Par3, have been found to be downregulated upon activation of NF-κB in intestinal epithelial cells. To determine their possible role in pro-inflammatory responses we transduced Caco-2 human colon carcinoma cells with constitutively active (ca) PKCι or a...

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Detalles Bibliográficos
Autores principales: Forteza, Radia, Wald, Flavia A., Mashukova, Anastasia, Kozhekbaeva, Zhanna, Salas, Pedro J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828774/
https://www.ncbi.nlm.nih.gov/pubmed/24244864
http://dx.doi.org/10.1242/bio.20135918