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Par-complex aPKC and Par3 cross-talk with innate immunity NF-κB pathway in epithelial cells
Components of the Par-complex, atypical PKC and Par3, have been found to be downregulated upon activation of NF-κB in intestinal epithelial cells. To determine their possible role in pro-inflammatory responses we transduced Caco-2 human colon carcinoma cells with constitutively active (ca) PKCι or a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828774/ https://www.ncbi.nlm.nih.gov/pubmed/24244864 http://dx.doi.org/10.1242/bio.20135918 |