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Long‐Term miR‐669a Therapy Alleviates Chronic Dilated Cardiomyopathy in Dystrophic Mice

BACKGROUND: Dilated cardiomyopathy (DCM) is a leading cause of chronic morbidity and mortality in muscular dystrophy (MD) patients. Current pharmacological treatments are not yet able to counteract chronic myocardial wastage, thus novel therapies are being intensely explored. MicroRNAs have been imp...

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Detalles Bibliográficos
Autores principales: Quattrocelli, Mattia, Crippa, Stefania, Montecchiani, Celeste, Camps, Jordi, Cornaglia, Antonia Icaro, Boldrin, Luisa, Morgan, Jennifer, Calligaro, Alberto, Casasco, Andrea, Orlacchio, Aldo, Gijsbers, Rik, D'Hooge, Jan, Toelen, Jaan, Janssens, Stefan, Sampaolesi, Maurilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828786/
https://www.ncbi.nlm.nih.gov/pubmed/23963759
http://dx.doi.org/10.1161/JAHA.113.000284