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Increased Atherosclerotic Lesions in LDL Receptor Deficient Mice With Hematopoietic Nuclear Receptor Rev‐erbα Knock‐ Down

BACKGROUND: Nuclear receptor Rev‐erbα plays important roles in circadian clock timing, lipid metabolism, adipogenesis, and vascular inflammation. However, the role of Rev‐erbα in atherosclerotic lesion development has not been assessed in vivo. METHODS AND RESULTS: The nuclear receptor Rev‐erbα was...

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Detalles Bibliográficos
Autores principales: Ma, Hongling, Zhong, Wenbin, Jiang, Yingliang, Fontaine, Coralie, Li, Shiqian, Fu, Jiangnan, Olkkonen, Vesa M., Staels, Bart, Yan, Daoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828791/
https://www.ncbi.nlm.nih.gov/pubmed/23963755
http://dx.doi.org/10.1161/JAHA.113.000235