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Mechanical load modulates chondrogenesis of human mesenchymal stem cells through the TGF-β pathway

This study investigated the effect of mechanical load on human mesenchymal stem cell (hMSC) differentiation under different exogenous transforming growth factor-β1 (TGF-β(1)) concentrations (0, 1 or 10 ng/ml).The role of the TGF-β signalling pathway in this process was also studied. Human MSCs were...

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Detalles Bibliográficos
Autores principales: Li, Zhen, Kupcsik, Laszlo, Yao, Shan-Jing, Alini, Mauro, Stoddart, Martin J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828850/
https://www.ncbi.nlm.nih.gov/pubmed/19432813
http://dx.doi.org/10.1111/j.1582-4934.2009.00780.x