PPARγ ligands inhibit telomerase activity and hTERT expression through modulation of the Myc/Mad/Max network in colon cancer cells

In human cells the length of telomeres depends on telomerase activity. This activity and the expression of the catalytic subunit of human telomerase reverse transcriptase (hTERT) is strongly up-regulated in most human cancers. hTERT expression is regulated by different transcription factors, such as...

Descripción completa

Detalles Bibliográficos
Autores principales: Toaldo, Cristina, Pizzimenti, Stefania, Cerbone, Angelo, Pettazzoni, Piergiorgio, Menegatti, Elisa, Daniela, Berardi, Minelli, Rosalba, Giglioni, Barbara, Dianzani, Mario Umberto, Ferretti, Carlo, Barrera, Giuseppina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828851/
https://www.ncbi.nlm.nih.gov/pubmed/19912441
http://dx.doi.org/10.1111/j.1582-4934.2009.00966.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828851/
https://www.ncbi.nlm.nih.gov/pubmed/19912441
http://dx.doi.org/10.1111/j.1582-4934.2009.00966.x

Ejemplares similares