Loss of MTG16a (CBFA2T3), a novel rDNA repressor, leads to increased ribogenesis and disruption of breast acinar morphogenesis

Mostrar otras versiones (1)

Human MTG16a (CBFA2T3), a chromatin repressor with nucleolar localization, was described to act as a suppressor of breast tumourigenesis. Here we show that MTG16a is a novel ribosomal gene repressor, which can counteract MYC-driven activation of ribosomal RNA (rRNA) transcription. We also show that...

Descripción completa

Detalles Bibliográficos
Autores principales: Rossetti, Stefano, Hoogeveen, André T, Esposito, Joseph, Sacchi, Nicoletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828852/
https://www.ncbi.nlm.nih.gov/pubmed/19961547
http://dx.doi.org/10.1111/j.1582-4934.2009.00982.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828852/
https://www.ncbi.nlm.nih.gov/pubmed/19961547
http://dx.doi.org/10.1111/j.1582-4934.2009.00982.x

Ejemplares similares