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PKR, the double stranded RNA-dependent protein kinase as a critical target in Alzheimer's disease
Amyloid β-peptide (Aβ) deposits and neurofibrillary tangles are key hallmarks in Alzheimer's disease (AD). Aβ stimulates many signal transducers involved in the neuronal death. However, many mechanisms remain to be elucidated because no definitive therapy of AD exists. Some studies have focused...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828860/ https://www.ncbi.nlm.nih.gov/pubmed/19602051 http://dx.doi.org/10.1111/j.1582-4934.2009.00849.x |