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PKR, the double stranded RNA-dependent protein kinase as a critical target in Alzheimer's disease

Amyloid β-peptide (Aβ) deposits and neurofibrillary tangles are key hallmarks in Alzheimer's disease (AD). Aβ stimulates many signal transducers involved in the neuronal death. However, many mechanisms remain to be elucidated because no definitive therapy of AD exists. Some studies have focused...

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Detalles Bibliográficos
Autores principales:	Morel, Milena, Couturier, Julien, Lafay-Chebassier, Claire, Paccalin, Marc, Page, Guylène
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2009
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828860/ https://www.ncbi.nlm.nih.gov/pubmed/19602051 http://dx.doi.org/10.1111/j.1582-4934.2009.00849.x

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