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Deficiency in TLR4 signal transduction ameliorates cardiac injury and cardiomyocyte contractile dysfunction during ischemia

Toll-like receptor 4 (TLR4), a proximal signalling receptor in innate immune responses to lipopolysaccharide of gram-negative pathogens, is expressed in the heart. Accumulating evidence have consolidated the notion that TLR4 plays an essential role in the pathogenesis of cardiac dysfunction. However...

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Detalles Bibliográficos
Autores principales:	Zhao, Peng, Wang, Jingying, He, Leilei, Ma, Heng, Zhang, Xiaoyu, Zhu, Xinglei, Dolence, E Kurt, Ren, Jun, Li, Ji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2009
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828863/ https://www.ncbi.nlm.nih.gov/pubmed/19508385 http://dx.doi.org/10.1111/j.1582-4934.2009.00798.x

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