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Death receptors as targets for anti-cancer therapy

Human tumour cells are characterized by their ability to avoid the normal regulatory mechanisms of cell growth, division and death. The classical chemotherapy aims to kill tumour cells by causing DNA damage-induced apoptosis. However, as many tumour cells posses mutations in intracellular apoptosis-...

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Detalles Bibliográficos
Autores principales: Papenfuss, Kerstin, Cordier, Stefanie M, Walczak, Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828874/
https://www.ncbi.nlm.nih.gov/pubmed/19210756
http://dx.doi.org/10.1111/j.1582-4934.2008.00514.x