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Sildenafil-mediated neovascularization and protection against myocardial ischaemia reperfusion injury in rats: role of VEGF/angiopoietin-1

Sildenafil citrate (SC), a drug for erectile dysfunction, is now emerging as a cardiopulmonary drug. Our study aimed to determine a novel role of sildenafil on cardioprotection through stimulating angiogenesis during ischaemia (I) reperfusion (R) at both capillary and arteriolar levels and to examin...

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Detalles Bibliográficos
Autores principales: Koneru, Srikanth, Varma Penumathsa, Suresh, Thirunavukkarasu, Mahesh, Vidavalur, Ramesh, Zhan, Lijun, Singal, Pawan K, Engelman, Richard M, Das, Dipak K, Maulik, Nilanjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828881/
https://www.ncbi.nlm.nih.gov/pubmed/18373738
http://dx.doi.org/10.1111/j.1582-4934.2008.00319.x