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ZHX2 is a repressor of α-fetoprotein expression in human hepatoma cell lines

The zinc-fingers and homeoboxes 2 (ZHX2) protein was shown previously to be involved in postnatal repression of α-fetoprotein (AFP) in mice. More recently, loss of ZHX2 expression was often found in human hepatcellular carcinoma (HCC), where AFP is frequently reactivated. Using HepG2 and HepG2.2.15,...

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Detalles Bibliográficos
Autores principales: Shen, H, Luan, F, Liu, H, Gao, L, Liang, X, Zhang, L, Sun, W, Ma, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828890/
https://www.ncbi.nlm.nih.gov/pubmed/18194454
http://dx.doi.org/10.1111/j.1582-4934.2008.00233.x