The Kazal motifs of RECK protein inhibit MMP-9 secretion and activity and reduce metastasis of lung cancer cells in vitro and in vivo

RECK is a membrane-anchored glycoprotein which may negatively regulate matrix metalloproteinase (MMP) activity to suppress tumor invasion and metastasis. In this study, recombinant proteins corresponding to the residues 285–368 (named as CKM which contained cysteine knot motif), 605–799 (named as K1...

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Detalles Bibliográficos
Autores principales: Chang, Chong-Keng, Hung, Wen-Chun, Chang, Hui-Chiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828891/
https://www.ncbi.nlm.nih.gov/pubmed/18194466
http://dx.doi.org/10.1111/j.1582-4934.2008.00215.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828891/
https://www.ncbi.nlm.nih.gov/pubmed/18194466
http://dx.doi.org/10.1111/j.1582-4934.2008.00215.x

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