Chondroitin sulphate decreases collagen synthesis in normal and scleroderma fibroblasts through a Smad-independent TGF-β pathway – implication of C-Krox and Sp1

Despite several investigations, the transcriptional mechanisms which regulate the expression of both type I collagen genes (COL1A1 and COL1A2) in either physiological or pathological situations, such as scleroderma, are not completely known. In this study, we determined the effects of both native ic...

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Detalles Bibliográficos
Autores principales: Renard, Emmanuelle, Chadjichristos, Christos, Kypriotou, Magdalini, Beauchef, Gallic, Bordat, Pascal, Dompmartin, Anne, Widom, Russell L, Boumediene, Karim, Pujol, Jean-Pierre, Galéra, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828896/
https://www.ncbi.nlm.nih.gov/pubmed/18298657
http://dx.doi.org/10.1111/j.1582-4934.2008.00287.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828896/
https://www.ncbi.nlm.nih.gov/pubmed/18298657
http://dx.doi.org/10.1111/j.1582-4934.2008.00287.x

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