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Anti-CD44 induces apoptosis in T lymphoma via mitochondrial depolarization
A blockade of CD44 can interfere with haematopoietic and leukemic stem cell homing, the latter being considered as a therapeutic option in haematological malignancies. We here aimed to explore the molecular mechanism underlying the therapeutic efficacy of anti-CD44. We noted that in irradiated mice...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829012/ https://www.ncbi.nlm.nih.gov/pubmed/19765170 http://dx.doi.org/10.1111/j.1582-4934.2009.00909.x |