Unfolded protein response suppresses CEBPA by induction of calreticulin in acute myeloid leukaemia

The unfolded protein response (UPR) is triggered by the accumulation of misfolded proteins within the endoplasmic reticulum (ER). The role of the UPR during leukemogenesis is unknown so far. Here, we studied the induction of mediators of the UPR in leukaemic cells of AML patients. Increased expressi...

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Detalles Bibliográficos
Autores principales: Schardt, Julian A, Eyholzer, Marianne, Timchenko, Nikolai A, Mueller, Beatrice U, Pabst, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829017/
https://www.ncbi.nlm.nih.gov/pubmed/19659458
http://dx.doi.org/10.1111/j.1582-4934.2009.00870.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829017/
https://www.ncbi.nlm.nih.gov/pubmed/19659458
http://dx.doi.org/10.1111/j.1582-4934.2009.00870.x

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