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Crosstalk between the NF-κB activating IKK-complex and the CSN signalosome

A great variety of signalling pathways regulating inflammation, cell development and cell survival require NF-κB transcription factors, which are normally inactive due to binding to inhibitors, such as IκBα. The canonical activation pathway of NF-κB is initiated by phosphorylation of the inhibitor b...

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Detalles Bibliográficos
Autores principales: Orel, Lukas, Neumeier, Hannah, Hochrainer, Karin, Binder, Bernd R, Schmid, Johannes A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829021/
https://www.ncbi.nlm.nih.gov/pubmed/19656241
http://dx.doi.org/10.1111/j.1582-4934.2009.00866.x