Parameters of oligonucleotide-mediated gene modification in mouse ES cells

Gene targeting by single-stranded oligodeoxyribonucleotides (ssODNs) is emerging as a powerful tool for the introduction of subtle gene modifications in mouse embryonic stem (ES) cells and the generation of mutant mice. Here, we have studied the role of ssODN composition, transcription and replicati...

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Detalles Bibliográficos
Autores principales: Aarts, Marieke, te Riele, Hein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829028/
https://www.ncbi.nlm.nih.gov/pubmed/19627401
http://dx.doi.org/10.1111/j.1582-4934.2009.00847.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829028/
https://www.ncbi.nlm.nih.gov/pubmed/19627401
http://dx.doi.org/10.1111/j.1582-4934.2009.00847.x

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