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Cognitive impairment in the Tg6590 transgenic rat model of Alzheimer’s disease

Recently, interest in the rat as an animal model of Alzheimer’s disease (AD) has been growing. We have previously described the Tg6590 transgenic rat line expressing the amyloid precursor protein containing the Swedish AD mutation (K670M/N671L) that shows early stages of Aβ deposition, predominantly...

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Detalles Bibliográficos
Autores principales: Kloskowska, Ewa, Pham, Therese M, Nilsson, Tatjana, Zhu, Shunwei, Öberg, Johanna, Codita, Alina, Pedersen, Lars Ø, Pedersen, Jan T, Malkiewicz, Katarzyna, Winblad, Bengt, Folkesson, Ronnie, Benedikz, Eirikur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829041/
https://www.ncbi.nlm.nih.gov/pubmed/19538474
http://dx.doi.org/10.1111/j.1582-4934.2009.00809.x