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Cognitive impairment in the Tg6590 transgenic rat model of Alzheimer’s disease
Recently, interest in the rat as an animal model of Alzheimer’s disease (AD) has been growing. We have previously described the Tg6590 transgenic rat line expressing the amyloid precursor protein containing the Swedish AD mutation (K670M/N671L) that shows early stages of Aβ deposition, predominantly...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829041/ https://www.ncbi.nlm.nih.gov/pubmed/19538474 http://dx.doi.org/10.1111/j.1582-4934.2009.00809.x |