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Reduction of circulating soluble Flt-1 alleviates preeclampsia-like symptoms in a mouse model
Preeclampsia (PE) is characterized by widespread endothelial damage with hypertension, proteinuria, glomeruloendotheliosis and elevated soluble Flt-1 (sFlt-1), a natural occurring antagonist of vascular endothelial growth factor (VEGF). Cancer patients receiving anti-VEGF therapy exhibit similar sym...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829045/ https://www.ncbi.nlm.nih.gov/pubmed/19538465 http://dx.doi.org/10.1111/j.1582-4934.2009.00820.x |