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DNMT1 and AIM1 Imprinting in human placenta revealed through a genome-wide screen for allele-specific DNA methylation

BACKGROUND: Genomic imprinting is an epigenetically regulated process wherein genes are expressed in a parent-of-origin specific manner. Many imprinted genes were initially identified in mice; some of these were subsequently shown not to be imprinted in humans. Such discrepancy reflects developmenta...

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Detalles Bibliográficos
Autores principales: Das, Radhika, Lee, Yew Kok, Strogantsev, Ruslan, Jin, Shengnan, Lim, Yen Ching, Ng, Poh Yong, Lin, Xueqin Michelle, Chng, Keefe, Yeo, George SH, Ferguson-Smith, Anne C, Ding, Chunming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829101/
https://www.ncbi.nlm.nih.gov/pubmed/24094292
http://dx.doi.org/10.1186/1471-2164-14-685