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Reversion of the Arabidopsis rpn12a-1 exon-trap mutation by an intragenic suppressor that weakens the chimeric 5’ splice site

Background: In the Arabidopsis 26S proteasome mutant rpn12a-1, an exon-trap T-DNA is inserted 531 base pairs downstream of the RPN12a STOP codon. We have previously shown that this insertion activates a STOP codon-associated latent 5' splice site that competes with the polyadenylation signal du...

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Detalles Bibliográficos
Autores principales: Kurepa, Jasmina, Li, Yan, Smalle, Jan A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829128/
https://www.ncbi.nlm.nih.gov/pubmed/24358894
http://dx.doi.org/10.12688/f1000research.2-60.v2