Solution NMR Analyses of the C-type Carbohydrate Recognition Domain of DC-SIGNR Protein Reveal Different Binding Modes for HIV-derived Oligosaccharides and Smaller Glycan Fragments

The C-type lectin DC-SIGNR (dendritic cell-specific ICAM-3-grabbing non-integrin-related; also known as L-SIGN or CD299) is a promising drug target due to its ability to promote infection and/or within-host survival of several dangerous pathogens (e.g. HIV and severe acute respiratory syndrome coron...

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Detalles Bibliográficos
Autores principales: Probert, Fay, Whittaker, Sara B.-M., Crispin, Max, Mitchell, Daniel A., Dixon, Ann M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Protein Structure and Folding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829359/
https://www.ncbi.nlm.nih.gov/pubmed/23788638
http://dx.doi.org/10.1074/jbc.M113.458299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829359/
https://www.ncbi.nlm.nih.gov/pubmed/23788638
http://dx.doi.org/10.1074/jbc.M113.458299

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