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FAM129B is a novel regulator of Wnt/β-catenin signal transduction in melanoma cells

The inability of targeted BRAF inhibitors to produce long-lasting improvement in the clinical outcome of melanoma highlights a need to identify additional approaches to inhibit melanoma growth. Recent studies have shown that activation of the Wnt/β-catenin pathway decreases tumor growth and cooperat...

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Detalles Bibliográficos
Autores principales: Conrad, Willliam, Major, Michael B, Cleary, Michele A, Ferrer, Marc, Roberts, Brian, Marine, Shane, Chung, Namjin, Arthur, William T, Moon, Randall T, Berndt, Jason D, Chien, Andy J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829391/
https://www.ncbi.nlm.nih.gov/pubmed/24358901
http://dx.doi.org/10.12688/f1000research.2-134.v2